SJTU ASIA-PACIFIC GRADUATE INSTITUTE

Carbon-Negative Synthetic Biology for Biomaterial Production from CO_₂

Light-driven negative carbon bioproduction: 1 STONE 3 BIRDS

CNSB-CREATE is a collaborative programme between Shanghai Jiao Tong University (SJTU) and National University of Singapore (NUS) under the Campus for Research Excellence and Technological Enterprise (CREATE) framework, which aims to build the highly efficient cell factory platform (using Synechococcus sp. PCC 11901) for the production of high-value biofuels such as 1,4-butanediol (BDO), and iso- butanol, with the following three specific objectives:

1To produce bio-based biofuels using CO₂ as the sole starting substrate with synthetic biology;
2To construct photosensitive materials-photosynthetic organism interfaces to augment photosynthetic efficiency with CO₂;
3To innovate and create breakthrough with the usage of microbes such as cyanobacteria for efficiently utilizing CO₂ and developing efficient microbial chassis to realize "light-driven cell factories" of green synthetic chemical production and simultaneously ease urgent environmental and energy pressures.